16 days in Spain, Northwest Italy & Amsterdam Itinerary

16 days in Spain, Northwest Italy & Amsterdam Itinerary

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Route & dates

16 days in Spain, Northwest Italy & Amsterdam Itinerary

Start: Detroit, United States
1
Seville, Spain
— 1 day
2
Madrid, Spain
— 2 nights
3
Barcelona, Spain
— 2 nights
Fly:  5​h 15​min
4
Rome, Italy
— 2 nights
5
Florence, Italy
— 2 nights
6
Venice, Italy
— 2 nights
Fly:  4​h 45​min
7
Amsterdam, Holland
— 3 nights
End: Detroit, United States

1
day
Seville, Spain

Seville ©
A city of rich Moorish heritage, Seville is the cultural and financial center of southern Spain, and the site of numerous festivals throughout the year.
Kick off your visit on the 8th (Wed): admire the natural beauty at Royal Alcázar of Seville, admire the landmark architecture of Plaza de España, then take in panoramic vistas at Torre Giralda, and finally get great views at Catedral de Sevilla.

To see ratings, photos, and more tourist information, go to the Seville route website .

Detroit, USA to Seville is an approximately 15-hour flight. You can also do a combination of bus and flight; or do a combination of flight and train. Due to the time zone difference, you'll lose 6 hours traveling from Detroit to Seville. In May, Seville is a bit warmer than Detroit - with highs of 79°F and lows of 58°F. Finish your sightseeing early on the 8th (Wed) to allow enough time to take a train to Madrid.

Things to do in Seville

Historic Sites Parks Museums
Find places to stay May 8 — 9:
Highlights from your plan
Plaza de España ©
Plaza de España
Royal Alcázar of Seville ©
Royal Alcázar of Seville
Catedral de Sevilla ©
Catedral de Sevilla

2
nights
Madrid, Spain

Madrid ©
Madrid is known for its cultural and artistic heritage, lively nightlife, and a dynamic culinary scene.
Start off your visit on the 9th (Thu): tour the pleasant surroundings at Retiro Park, then examine the collection at Prado National Museum, and then admire the masterpieces at Museo Nacional Centro de Arte Reina Sofia. Here are some ideas for day two: admire the striking features of Plaza Mayor, then admire the masterpieces at Royal Palace of Madrid, and then examine the collection at Museo Nacional Thyssen-Bornemisza.

Find out how to plan Madrid trip without stress by asking Inspirock to help create an itinerary.

Getting from Seville to Madrid by train takes about 3 hours. Other options: fly; or drive. Expect little chillier evenings in Madrid when traveling from Seville in May, with lows around 52°F. Wrap up your sightseeing on the 10th (Fri) early enough to take a train to Barcelona.

Things to do in Madrid

Museums Historic Sites Parks
Find places to stay May 8 — 10:
Highlights from your plan
Prado National Museum ©
Prado National Museum
Parque del Retiro ©
Parque del Retiro
Royal Palace of Madrid ©
Royal Palace of Madrid

2
nights
Barcelona, Spain

Barcelona ©
Barcelona, the country’s second-largest city, is a cosmopolitan urban center known for its throbbing youthful energy and stellar architecture.
Kick off your visit on the 11th (Sat): walk around Parc Guell, then admire the striking features of Basilica of the Sagrada Familia, and then don't miss a visit to Las Ramblas. On your second day here, pause for some serene contemplation at Barcelona Cathedral, then take a stroll through El Barri Gòtic, then examine the collection at Casa Batllo, and finally pause for some photo ops at Casa Mila - La Pedrera.

For traveler tips, maps, more things to do, and tourist information, read our Barcelona day trip planning app .

You can take a train from Madrid to Barcelona in 3 hours. Alternatively, you can fly; or drive. In May in Barcelona, expect temperatures between 71°F during the day and 57°F at night. Wrap up your sightseeing on the 12th (Sun) to allow time to travel to Rome.

Things to do in Barcelona

Historic Sites Museums Parks
Find places to stay May 10 — 12:
Highlights from your plan
Basilica of the Sagrada Familia ©
Basilica of the Sagrada Familia
Parc Guell ©
Parc Guell
Casa Batllo ©
Casa Batllo

2
nights
Rome, Italy

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Rome is known for historic sites, nightlife, museums, classes, and shopping. Your plan includes some of its best attractions: delve into the distant past at Colosseum, take an in-depth tour of Musei Capitolini, contemplate the long history of St. Peter's Basilica, and wander the streets of Trastevere.

To find maps, more things to do, traveler tips, and tourist information, read Rome trip itinerary planning tool .

Traveling by flight from Barcelona to Rome takes 5.5 hours. Alternatively, you can drive; or take a train. May in Rome sees daily highs of 75°F and lows of 58°F at night. Cap off your sightseeing on the 15th (Wed) early enough to catch the train to Florence.

Things to do in Rome

Historic Sites Museums Neighborhoods

Side Trip

Vatican City
Find places to stay May 12 — 15:
Highlights from your plan
Colosseum ©
Colosseum
Trevi Fountain ©
Trevi Fountain
Pantheon ©
Pantheon

2
nights
Florence, Italy

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
On the 16th (Thu), get great views at Piazzale Michelangelo, examine the collection at Pitti Palace, then explore the world behind art at Uffizi Galleries, and finally take in the views from Ponte Vecchio. Get ready for a full day of sightseeing on the 17th (Fri): examine the collection at Academy Of Florence Art Gallery, take an in-depth tour of Basilica di Santa Croce, get to know the fascinating history of Piazza del Duomo, then take in the spiritual surroundings of Cathedral of Santa Maria del Fiore, then appreciate the history behind Campanile di Giotto, and finally contemplate in the serene atmosphere at The Baptistery of St. John.

To see reviews, where to stay, photos, and more tourist information, read Florence route planning site .

You can take a train from Rome to Florence in 2 hours. Other options are to drive; or fly. Traveling from Rome in May, you can expect nighttime temperatures to be a bit cooler in Florence, with lows of 52°F. Finish your sightseeing early on the 17th (Fri) so you can take a train to Venice.

Things to do in Florence

Museums Historic Sites
Find places to stay May 15 — 17:
Highlights from your plan
Gallerie Degli Uffizi ©
Gallerie Degli Uffizi
Academy Of Florence Art Gallery ©
Academy Of Florence Art Gallery
Cathedral of Santa Maria del Fiore ©

2
nights
Venice, Italy

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Kick off your visit on the 18th (Sat): admire the striking features of Basilica di San Marco, then explore the world behind art at Peggy Guggenheim Collection, then admire the landmark architecture of Doge's Palace, and finally explore the activities along Canal Grande. Get ready for a full day of sightseeing on the next day: snap pictures at Ponte di Rialto, take in the views from Ponte dei Sospiri, then appreciate the extensive heritage of St. Mark's Square, and finally admire the masterpieces at Gallerie dell'Accademia.

To find photos, reviews, and tourist information, read our Venice holiday planner.

You can take a train from Florence to Venice in 2.5 hours. Other options are to drive; or take a bus. In May, daily temperatures in Venice can reach 72°F, while at night they dip to 55°F. Wrap up your sightseeing on the 19th (Sun) to allow time to travel to Amsterdam.

Things to do in Venice

Historic Sites Museums Nature
Find places to stay May 17 — 19:
Highlights from your plan
Doge's Palace ©
Doge's Palace
Canal Grande ©
Canal Grande
Basilica di San Marco
Basilica di San Marco

3
nights
Amsterdam, Holland

Amsterdam ©
Known as one of the greatest small cities in the world, Amsterdam charms visitors with its cool and cozy atmosphere.
Amsterdam is known for museums, nightlife, parks, breweries & distilleries, and shopping. Your plan includes some of its best attractions: get engrossed in the history at Van Gogh Museum, explore the world behind art at Museum Het Rembrandthuis (Rembrandt House), meet the residents at ARTIS, and sample the tasty concoctions at Heineken Experience.

To find photos, maps, more things to do, and tourist information, go to the Amsterdam vacation planning tool .

Fly from Venice to Amsterdam in 5 hours. Alternatively, you can do a combination of train and flight; or drive. Traveling from Venice in May, expect Amsterdam to be a bit cooler, temps between 63°F and 48°F. Wrap up your sightseeing on the 22nd (Wed) to allow time to travel back home.

Things to do in Amsterdam

Museums Parks Zoos & Aquariums
Find places to stay May 19 — 22:
Highlights from your plan
Van Gogh Museum ©
Van Gogh Museum
Rijksmuseum ©
Rijksmuseum
Anne Frank House ©
Anne Frank House

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